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(Q21986950)
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English
Transducin-like enhancer of split 3
mammalian protein found in Mus musculus
grg-3
Tle3
transducin-like enhancer protein 3
ESG
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q08122
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q08122
part of
WD40/YVTN repeat-like-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q08122
WD40-repeat-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q08122
Groucho/transducin-like enhancer
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q08122
Groucho/TLE, N-terminal Q-rich domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
WD40 repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
WD40 repeat, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q08122
encoded by
Tle3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q08122
molecular function
protein binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IPI
transcription corepressor activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IBA
cell component
nucleoplasm
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
beta-catenin-TCF complex
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
nucleus
determination method
IEA
ISO
4 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08122&geneProductId=UniProtKB:Q08122
determination method
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08122&geneProductId=UniProtKB:Q08122
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08122&geneProductId=UniProtKB:Q08122
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08122&geneProductId=UniProtKB:Q08122
determination method
IEA
nucleus
determination method
IBA
IEA
ISO
5 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IBA
transcription regulator complex
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IBA
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
Wnt signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08122&geneProductId=UniProtKB:Q08122
determination method
IEA
spermatogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q08122
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
negative regulation of canonical Wnt signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IBA
negative regulation of cold-induced thermogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs
GOA
curator
YuBioLab
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IMP
negative regulation of nucleic acid-templated transcription
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08122
determination method
IEA
has part(s)
WD40 repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q08122
WD40 repeat, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q08122
Groucho/TLE, N-terminal Q-rich domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q08122
Identifiers
RefSeq protein ID
NP_001077396
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
NP_001077397
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
NP_033415
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511088
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511089
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511090
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511091
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511092
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511093
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_006511094
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_017168766
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_017168767
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_017168768
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
XP_036010732
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21887
UniProt protein ID
Q08122
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q08122
Ensembl protein ID
ENSMUSP00000124131
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124131
ENSMUSP00000124173
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124173
ENSMUSP00000124977
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124977
ENSMUSP00000034820
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000034820
ENSMUSP00000123723
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000123723
ENSMUSP00000124055
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124055
ENSMUSP00000124150
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124150
ENSMUSP00000124158
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124158
ENSMUSP00000124432
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124432
ENSMUSP00000124557
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000124557
ENSMUSP00000125011
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125011
ENSMUSP00000125032
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125032
ENSMUSP00000125049
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125049
ENSMUSP00000125537
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125537
ENSMUSP00000136010
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000136010
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