(Q21987378)

http://www.ebi.ac.uk/interpro/protein/P55086

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

G-protein beta-subunit binding

1 reference

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

G-protein alpha-subunit binding

1 reference

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

thrombin-activated receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

heterotrimeric G-protein binding

1 reference

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

G protein-coupled receptor activity

TAS

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

24 April 2018

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

G protein-coupled receptor activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

integral component of membrane

IBA

cell component

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

1 reference

14 February 2019

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

integral component of plasma membrane

3 references

innate immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of chemotaxis

1 reference

14 February 2019

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of pseudopodium assembly

1 reference

14 February 2019

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-gamma-dependent pathway

leukocyte proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of cell migration

1 reference

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

immune system process

1 reference

14 February 2019

T cell activation involved in immune response

1 reference

14 February 2019

Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of renin secretion into blood stream

1 reference

14 February 2019

Proteinase-activated receptors 1 and 2 exert opposite effects on renal renin release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

thrombin-activated receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

inflammatory response

1 reference

14 February 2019

regulation of JNK cascade

neutrophil activation

3 references

3 references

defense response to virus

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-gamma-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of I-kappaB kinase/NF-kappaB signaling

3 references

positive regulation of superoxide anion generation

3 references

3 references

regulation of I-kappaB kinase/NF-kappaB signaling

3 references

positive regulation of cytosolic calcium ion concentration

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of Rho protein signal transduction

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

24 April 2018

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55086&geneProductId=UniProtKB:P55086

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of ERK1 and ERK2 cascade

IBA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

mature conventional dendritic cell differentiation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

G protein-coupled receptor signaling pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

positive regulation of glomerular filtration

3 references

positive regulation of Rho protein signal transduction

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55086

GPCR, rhodopsin-like, 7TM

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0