Wikidata

(Q21987767)

English

Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

mammalian protein found in Mus musculus

  • T-cell transcription factor NFAT3
  • Nfatc4
  • nuclear factor of activated T-cells, cytoplasmic 4
  • NF-ATc4
  • NF-AT3
  • transcription complex subunit NF-ATc4
In more languages

Statements

molecular function
DNA-binding transcription factor activity
determination method
IBA
IDA
IEA
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
14 February 2019
stated in
Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Requirement of transcription factor NFAT in developing atrial myocardium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IBA
cell component
nucleus
determination method
IDA
IEA
ISO
7 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8K120
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
24 April 2018
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
24 April 2018
stated in
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
24 April 2018
stated in
Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
24 April 2018
stated in
p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8K120
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
14 February 2019
stated in
Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus.
GOA
curator
UniProt
UniProt protein ID
Q8K120
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IBA
cytosol
determination method
IBA
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IEA
retrieved
14 February 2019
stated in
Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus.
GOA
curator
UniProt
UniProt protein ID
Q8K120
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
IGI
IMP
7 references
retrieved
24 April 2018
stated in
Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IMP
retrieved
24 April 2018
stated in
p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IMP
retrieved
24 April 2018
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IGI
retrieved
24 April 2018
stated in
Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IGI
retrieved
24 April 2018
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
24 April 2018
stated in
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
24 April 2018
stated in
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K120&geneProductId=UniProtKB:Q8K120
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IGI
IMP
8 references
retrieved
14 February 2019
stated in
p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IMP
retrieved
14 February 2019
stated in
Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IMP
retrieved
14 February 2019
stated in
Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IGI
retrieved
14 February 2019
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IGI
retrieved
14 February 2019
stated in
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K120
determination method
IBA

Identifiers

 
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