(Q21988398)

English

Paired box 2

mammalian protein found in Mus musculus

Pax2
paired box gene 2
optic disc coloboma
paired box protein Pax-2

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Homeobox-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32114

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32114

Paired-box protein 2 C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Paired domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

DNA-binding transcription factor activity

determination method

1 reference

14 January 2019

Pax genes and their role in organogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32114&geneProductId=UniProtKB:P32114

determination method

superoxide-generating NAD(P)H oxidase activity

determination method

1 reference

24 April 2018

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32114&geneProductId=UniProtKB:P32114

determination method

transcription factor binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

determination method

1 reference

24 April 2018

Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32114&geneProductId=UniProtKB:P32114

determination method

C2H2 zinc finger domain binding

determination method

1 reference

14 February 2019

Repression of Pax-2 by WT1 during normal kidney development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

1 reference

14 February 2019

Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

DNA-binding transcription factor activity

determination method

microtubule organizing center

determination method

2 references

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Deficiency of intrarenal angiotensin II type 2 receptor impairs paired homeo box-2 and N-myc expression during nephrogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Differential expression of Hoxa-2 protein along the dorsal-ventral axis of the developing and adult mouse spinal cord

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

centriolar satellite

determination method

2 references

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

Golgi apparatus

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

transcription regulator complex

determination method

1 reference

14 February 2019

Pax genes and their role in organogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

protein-DNA complex

determination method

1 reference

14 February 2019

A Hox-Eya-Pax complex regulates early kidney developmental gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

protein-containing complex

determination method

1 reference

14 February 2019

A Hox-Eya-Pax complex regulates early kidney developmental gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

biological process

mesonephric tubule formation

determination method

1 reference

14 February 2019

Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cellular response to retinoic acid

determination method

1 reference

14 February 2019

Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

ureteric bud development

determination method

1 reference

14 February 2019

Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

optic nerve morphogenesis

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

determination method

1 reference

14 February 2019

Nephric lineage specification by Pax2 and Pax8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

ureter morphogenesis

determination method

1 reference

7 November 2018

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32114&geneProductId=UniProtKB:P32114

determination method

mesenchymal to epithelial transition involved in metanephros morphogenesis

determination method

1 reference

14 February 2019

Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cellular response to mechanical stimulus

determination method

1 reference

14 February 2019

PAX2 is reactivated in urinary tract obstruction and partially protects collecting duct cells from programmed cell death

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

optic cup morphogenesis involved in camera-type eye development

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

metanephric collecting duct development

determination method

1 reference

14 February 2019

PAX2 suppresses apoptosis in renal collecting duct cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cellular response to glucose stimulus

determination method

regulation of apoptotic process

determination method

1 reference

14 February 2019

Nephric lineage specification by Pax2 and Pax8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cochlea development

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

dopaminergic neuron differentiation

determination method

1 reference

14 February 2019

The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

renal system development

determination method

1 reference

7 November 2018

Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for Pax2 and Emx2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32114&geneProductId=UniProtKB:P32114

determination method

positive regulation of branching involved in ureteric bud morphogenesis

determination method

3 references

14 February 2019

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of metanephric DCT cell differentiation

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

reactive oxygen species metabolic process

determination method

1 reference

14 February 2019

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of mesenchymal cell apoptotic process involved in metanephros development

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

metanephric nephron tubule formation

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of transcription, DNA-templated

determination method

10 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Nephric lineage specification by Pax2 and Pax8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

PAX2 activates WNT4 expression during mammalian kidney development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

A Hox-Eya-Pax complex regulates early kidney developmental gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 overexpression in embryoid bodies induces upregulation of integrin alpha8 and aquaporin-1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

central nervous system development

determination method

1 reference

14 February 2019

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

branching involved in ureteric bud morphogenesis

determination method

paramesonephric duct development

determination method

1 reference

14 February 2019

Requirement of Lim1 for female reproductive tract development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of programmed cell death

determination method

1 reference

14 February 2019

Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

pancreas development

determination method

1 reference

14 February 2019

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

vestibulocochlear nerve formation

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

camera-type eye development

determination method

1 reference

14 February 2019

Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

mesodermal cell fate specification

determination method

1 reference

14 February 2019

A Hox-Eya-Pax complex regulates early kidney developmental gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of cytolysis

determination method

2 references

brain morphogenesis

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

pronephros development

determination method

1 reference

14 February 2019

Nephric lineage specification by Pax2 and Pax8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

regulation of metanephric nephron tubule epithelial cell differentiation

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cell differentiation

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

ureter development

determination method

1 reference

14 February 2019

Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of apoptotic process involved in metanephric collecting duct development

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of epithelial cell proliferation

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

metanephric mesenchymal cell differentiation

determination method

1 reference

14 February 2019

PAX2 activates WNT4 expression during mammalian kidney development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

metanephric epithelium development

determination method

1 reference

14 February 2019

Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of apoptotic process

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

PAX2 suppresses apoptosis in renal collecting duct cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

PAX2 is reactivated in urinary tract obstruction and partially protects collecting duct cells from programmed cell death

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

glial cell differentiation

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Vax genes ventralize the embryonic eye

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

nephric duct formation

determination method

1 reference

14 February 2019

Nephric lineage specification by Pax2 and Pax8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

retinal pigment epithelium development

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

stem cell differentiation

determination method

1 reference

14 February 2019

Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

metanephric distal convoluted tubule development

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

optic nerve structural organization

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of metanephric glomerulus development

determination method

1 reference

14 February 2019

Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

negative regulation of apoptotic process involved in metanephric nephron tubule development

determination method

1 reference

14 February 2019

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

ureter maturation

determination method

1 reference

14 February 2019

Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of optic nerve formation

determination method

1 reference

14 February 2019

Optic nerve axon number in mouse is regulated by PAX2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

metanephric mesenchyme development

determination method

1 reference

14 February 2019

Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

optic chiasma development

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

regulation of programmed cell death

determination method

1 reference

14 February 2019

Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

protein kinase B signaling

determination method

1 reference

14 February 2019

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

pronephric field specification

determination method

1 reference

14 February 2019

Nephric lineage specification by Pax2 and Pax8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

neural tube closure

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

inner ear morphogenesis

determination method

4 references

14 February 2019

The role of Pax2 in mouse inner ear development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cochlea morphogenesis

determination method

3 references

14 February 2019

Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cell fate determination

determination method

1 reference

14 February 2019

Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

optic nerve development

determination method

1 reference

14 February 2019

Pax2 contributes to inner ear patterning and optic nerve trajectory

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of transcription by RNA polymerase II

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

14 February 2019

Pax-2 interacts with RB and reverses its repression on the promoter of Rig-1, a Robo member

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

cellular response to hydrogen peroxide

determination method

1 reference

14 February 2019

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

mesenchymal to epithelial transition

determination method

1 reference

14 February 2019

Pax-2 controls multiple steps of urogenital development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

positive regulation of cell population proliferation

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32114

determination method

animal organ development

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32114&geneProductId=UniProtKB:P32114

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32114

Paired-box protein 2 C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32114

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Sitelinks

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