(Q21988399)

English

Paired box 4

mammalian protein found in Mus musculus

Pax4
paired box gene 4
paired box protein Pax-4

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Homeobox-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32115

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32115

Paired box protein Pax-4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32115

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Paired domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

14 February 2019

Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

sequence-specific DNA binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

Pax genes and their role in organogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

2 references

24 April 2018

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32115&geneProductId=UniProtKB:P32115

determination method

14 February 2019

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

transcription regulator complex

determination method

1 reference

14 February 2019

Pax genes and their role in organogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

determination method

3 references

biological process

cell differentiation

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

negative regulation of transcription by RNA polymerase II

determination method

2 references

14 February 2019

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

14 February 2019

Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

transcription, DNA-templated

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32115&geneProductId=UniProtKB:P32115

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

retina development in camera-type eye

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

circadian rhythm

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

positive regulation of cell differentiation

determination method

1 reference

14 February 2019

The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

animal organ morphogenesis

determination method

1 reference

14 February 2019

Pax genes and their role in organogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

regulation of cell differentiation

determination method

1 reference

14 February 2019

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

response to cAMP

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

endocrine pancreas development

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

pancreas development

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32115

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32115

Homeobox domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32115

Homeobox, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32115

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000031718

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000031718

ENSMUSP00000131301

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000131301

ENSMUSP00000126000

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126000

ENSMUSP00000134470

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000134470

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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