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Pre B cell leukemia homeobox 3
mammalian protein found in Mus musculus
homeobox protein PBX3
pre-B-cell leukemia transcription factor 3
Pbx3
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O35317
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
O35317
part of
Homeobox-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O35317
Homeobox domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
PBX domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O35317
encoded by
Pbx3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O35317
molecular function
DNA-binding transcription factor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
RNA polymerase II cis-regulatory region sequence-specific DNA binding
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
DNA binding
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O35317
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
sequence-specific DNA binding
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
retrieved
14 February 2019
stated in
Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IDA
2 references
retrieved
11 October 2018
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O35317&geneProductId=UniProtKB:O35317
determination method
IDA
retrieved
14 February 2019
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
5 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O35317
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
retrieved
14 February 2019
stated in
Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
retrieved
14 February 2019
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
retrieved
14 February 2019
stated in
Pbx3 is required for normal locomotion and dorsal horn development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
transcription regulator complex
determination method
IDA
2 references
retrieved
14 February 2019
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
retrieved
14 February 2019
stated in
The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
biological process
regulation of respiratory gaseous exchange by nervous system process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
In vitro visualization of respiratory neuron activity in the newborn mouse ventral medulla
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IMP
adult locomotory behavior
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Pbx3 is required for normal locomotion and dorsal horn development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IMP
dorsal spinal cord development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Pbx3 is required for normal locomotion and dorsal horn development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IMP
neuron development
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Pbx3 is required for normal locomotion and dorsal horn development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IMP
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O35317
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O35317&geneProductId=UniProtKB:O35317
determination method
IEA
respiratory gaseous exchange by respiratory system
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IMP
positive regulation of transcription by RNA polymerase II
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Pbx3 deficiency results in central hypoventilation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35317
determination method
IDA
transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O35317&geneProductId=UniProtKB:O35317
determination method
IEA
has part(s)
Homeobox domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O35317
PBX
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O35317
Homeobox, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O35317
Identifiers
RefSeq protein ID
NP_001277505
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18516
NP_058048
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18516
XP_006497845
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18516
XP_006497847
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18516
XP_030104280
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18516
XP_036015415
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18516
UniProt protein ID
O35317
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
O35317
Ensembl protein ID
ENSMUSP00000045281
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000045281
ENSMUSP00000108757
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000108757
ENSMUSP00000114695
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000114695
ENSMUSP00000115710
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000115710
ENSMUSP00000119914
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000119914
ENSMUSP00000123567
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000123567
ENSMUSP00000135226
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000135226
ENSMUSP00000135838
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000135838
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