(Q21988456)

http://www.ebi.ac.uk/interpro/protein/O88531

Alpha/Beta hydrolase fold

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O88531

1 reference

25 May 2022

1 reference

25 May 2022

palmitoyl hydrolase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

palmitoyl-(protein) hydrolase activity

IEA

8 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

1 reference

14 February 2019

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

palmitoyl-CoA hydrolase activity

IPI

3 references

palmitoyl-(protein) hydrolase activity

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

Developmental expression of palmitoyl protein thioesterase in normal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

3 references

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

Behavioral assessment in mouse models of neuronal ceroid lipofuscinosis using a light-cued T-maze

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

regulation of phospholipase A2 activity

1 reference

14 February 2019

Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

cellular macromolecule catabolic process

1 reference

14 February 2019

Characterization of lipid-linked oligosaccharide accumulation in mouse models of Batten disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

lysosome organization

neurotransmitter secretion

1 reference

14 February 2019

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

1 reference

14 February 2019

Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

protein depalmitoylation

6 references

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88531&geneProductId=UniProtKB:O88531

receptor-mediated endocytosis

IEA

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

lysosomal lumen acidification

IEA

3 references

nervous system development

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

3 references

lipid catabolic process

3 references

negative regulation of cell growth

3 references

membrane raft organization

3 references

negative regulation of apoptotic process

3 references

negative regulation of neuron apoptotic process

3 references

positive regulation of receptor-mediated endocytosis

3 references

positive regulation of pinocytosis

3 references

protein depalmitoylation

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88531