(Q21988710)

Cytoplasmic protein NCK

1 reference

SH2 domain superfamily

1 reference

Nck2, SH2 domain, protein family

1 reference

SH2 domain, protein family

1 reference

Nck2, SH3 domain 2, protein family

1 reference

Nck2, SH3 domain 3, protein family

1 reference

Nck2, SH3 domain 1, protein family

1 reference

SH3 domain, protein family

1 reference

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

1 reference

25 May 2022

1 reference

25 May 2022

scaffold protein binding

1 reference

14 February 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

protein-containing complex binding

IPI

1 reference

14 February 2019

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

1 reference

14 February 2019

Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

IDA

endoplasmic reticulum

3 references

3 references

1 reference

14 February 2019

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

TAS

biological process

1 reference

14 February 2019

Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

actin filament organization

1 reference

14 February 2019

The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

ephrin receptor signaling pathway

IMP

1 reference

14 February 2019

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

positive regulation of translation in response to endoplasmic reticulum stress

IDA

1 reference

14 February 2019

Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

14 February 2019

Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

14 February 2019

Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

1 reference

14 February 2019

The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

negative regulation of PERK-mediated unfolded protein response

IMP

1 reference

14 February 2019

Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

regulation of translation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

IEA

1 reference

14 February 2019

Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

lamellipodium assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55033

1 reference

SH3 domain

1 reference

Nck2, SH3 domain 3

1 reference

Nck2, SH3 domain 1

1 reference

Nck2, SH3 domain 2

1 reference

Nck2, SH2 domain

1 reference