(Q21988814)

P-loop containing nucleoside triphosphate hydrolase

1 reference

Tetratricopeptide repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

1 reference

14 February 2019

Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

ciliary inversin compartment

IDA

1 reference

14 February 2019

Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

16 July 2018

Targeting of Nphp3 to the primary cilia is controlled by an N-terminal myristoylation site and coiled-coil domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

3 references

regulation of Wnt signaling pathway, planar cell polarity pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

1 reference

14 February 2019

Abnormal lipid and fatty acid compositions of kidneys from mice with polycystic kidney disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

extracellular matrix organization

IMP

1 reference

14 February 2019

Altered extracellular matrix component gene expression in murine polycystic kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

IMP

Wnt signaling pathway

1 reference

14 February 2019

establishment or maintenance of cell polarity

1 reference

14 February 2019

3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

non-motile cilium assembly

IMP

1 reference

14 February 2019

3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

determination of left/right symmetry

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

maintenance of animal organ identity

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6

negative regulation of canonical Wnt signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

atrial septum development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

determination of pancreatic left/right asymmetry

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

photoreceptor cell maintenance

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

convergent extension involved in gastrulation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

determination of intestine left/right asymmetry

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

determination of stomach left/right asymmetry

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

determination of liver left/right asymmetry

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6

has part(s)

tetratricopeptide repeat

1 reference

Tetratricopeptide repeat-containing domain

1 reference