(Q21988947)

English

Protease (prosome, macropain) 26S subunit, ATPase 1

mammalian protein found in Mus musculus

proteasome 26S subunit ATPase 1
26S proteasome AAA-ATPase subunit RPT2
Psmc1
26S protease regulatory subunit 4
26S proteasome regulatory subunit 4

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Statements

1 reference

25 May 2022

26S Proteasome regulatory subunit 4

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P62192

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P62192

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

ATPase, AAA-type, core domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

AAA proteins

1 reference

based on heuristic

inferred from protein domain or family

Proteasomal ATPase OB C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ATPase, AAA-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

2 references

TBP-class protein binding

nuclear proteasome complex

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62192&geneProductId=UniProtKB:P62192

cytosolic proteasome complex

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62192&geneProductId=UniProtKB:P62192

determination method

IBA

proteasome regulatory particle, base subcomplex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

determination method

IBA

proteasome regulatory particle

1 reference

8 April 2019

PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

determination method

IDA

proteasome accessory complex

1 reference

8 April 2019

Mapping the murine cardiac 26S proteasome complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

determination method

IEA

biological process

positive regulation of RNA polymerase II transcription preinitiation complex assembly

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62192&geneProductId=UniProtKB:P62192

determination method

IBA

protein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

determination method

IEA

ubiquitin-dependent ERAD pathway

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62192&geneProductId=UniProtKB:P62192

determination method

IBA

negative regulation of neuron death

1 reference

8 April 2019

Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

determination method

IGI

positive regulation of proteasomal protein catabolic process

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62192

determination method

IEA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q21988947)

Protease (prosome, macropain) 26S subunit, ATPase 1

Statements

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