(Q28585769)

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Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein

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PubMed publication ID

31 January 2017

Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein (English)

1 reference

PubMed publication ID

31 January 2017

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Protease (prosome, macropain) 26S subunit, ATPase 1

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

neurodegeneration

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based on heuristic

inferred from title

author name string

Simon M. L. Paine

1

1 reference

PubMed publication ID

31 January 2017

Glenn Anderson

2

1 reference

PubMed publication ID

31 January 2017

Karen Bedford

3

1 reference

PubMed publication ID

31 January 2017

Karen Lawler

4

1 reference

PubMed publication ID

31 January 2017

R. John Mayer

5

1 reference

PubMed publication ID

31 January 2017

James Lowe

6

1 reference

PubMed publication ID

31 January 2017

Lynn Bedford

7

1 reference

PubMed publication ID

31 January 2017

language of work or name

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publication date

1 January 2013

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PubMed publication ID

31 January 2017

1 reference

PubMed publication ID

31 January 2017

8

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PubMed publication ID

31 January 2017

1

1 reference

PubMed publication ID

31 January 2017

e54711

1 reference

PubMed publication ID

31 January 2017

copyright license

Creative Commons Attribution 4.0 International

30 January 2013

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3559752/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Ubiquitin-dependent mitochondrial protein degradation

1 reference

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17 March 2017

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

1 reference

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17 March 2017

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

17 March 2017

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

17 March 2017

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

17 March 2017

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 reference

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17 March 2017

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

1 reference

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17 March 2017

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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17 March 2017

Aggresomes: a cellular response to misfolded proteins

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17 March 2017

Alpha-synuclein in Lewy bodies

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17 March 2017

Subregion- and cell type-restricted gene knockout in mouse brain

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17 March 2017

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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7 April 2017

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

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7 April 2017

Autophagy gone awry in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

7 April 2017

Proteasomes and their kin: proteases in the machine age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

7 April 2017

The 26S proteasome: a molecular machine designed for controlled proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

7 April 2017

Control of memory formation through regulated expression of a CaMKII transgene

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7 April 2017

The Parkinson's disease-related genes act in mitochondrial homeostasis

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29 September 2017

The Lewy body in Parkinson's disease and related neurodegenerative disorders

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29 September 2017

Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways

1 reference

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29 September 2017

Interaction of α-synuclein with vesicles that mimic mitochondrial membranes

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29 September 2017

Neurodegeneration as a consequence of failed mitochondrial maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Parkinson's disease and α-synuclein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Neuropathology underlying clinical variability in patients with synucleinopathies

1 reference

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29 September 2017

Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Mitochondrial contribution to Parkinson's disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Recent advances in the genetics of Parkinson's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Parkin uses the UPS to ship off dysfunctional mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Ubiquitin: same molecule, different degradation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Genetic analysis of pathways to Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Protein homeostasis and aging in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Genetic animal models of Parkinson's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Complex I: inhibitors, inhibition and neurodegeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

A critical evaluation of the ubiquitin-proteasome system in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction

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29 September 2017

Classification and basic pathology of Alzheimer disease

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29 September 2017

A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain

1 reference

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29 September 2017

In vivo alpha-synuclein overexpression in rodents: a useful model of Parkinson's disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Proteasomes: machines for all reasons

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Proteasome inhibition and Parkinson's disease modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Proteasome-associated proteins: regulation of a proteolytic machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

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29 September 2017

Methods for monitoring autophagy

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29 September 2017

Lewy-body formation is an aggresome-related process: a hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

29 September 2017

Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

3 June 2018

To aggregate or not to aggregate? A new role for p62.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

3 June 2018

Prevalence of Lewy bodies in Alzheimer's disease.

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3 June 2018

Relationships between Lewy bodies and pale bodies in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

3 June 2018

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3559752

28 July 2018

Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Involvement of macroautophagy in the dissolution of neuronal inclusions.

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21 January 2018

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Reproducible nigral cell loss after systemic proteasomal inhibitor administration to rats.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Proteasomal inhibition by alpha-synuclein filaments and oligomers.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Proteasome dysfunction in aged human alpha-synuclein transgenic mice.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054711

21 January 2018

Proteomic identification of novel proteins in cortical lewy bodies.

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21 January 2018

Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria

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21 January 2018

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

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21 January 2018

Mitochondrial dysfunction in Parkinson's disease

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21 January 2018

Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse.

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27 November 2018

Degradation of alpha-synuclein by proteasome

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https://pubmed.ncbi.nlm.nih.gov/23382946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23382946

12 December 2020

based on heuristic

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Effects of systemic PSI administration on catecholaminergic cells in the brain, adrenal medulla and carotid body in Wistar rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23382946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0054711

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2013PLoSO...854711P

0 references

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1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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