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(Q21989164)
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Secreted frizzled-related sequence protein 5
mammalian protein found in Mus musculus
sFRP-5
Sfrp5
secreted frizzled-related protein 5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9WU66
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q9WU66
part of
Tissue inhibitor of metalloproteinases-like, OB-fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9WU66
Secreted frizzled-related protein 5
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9WU66
Frizzled cysteine-rich domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9WU66
Frizzled domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Netrin module, non-TIMP type, protein family
1 reference
based on heuristic
inferred from protein domain or family
Netrin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9WU66
encoded by
Sfrp5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9WU66
molecular function
G protein-coupled receptor activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU66&geneProductId=UniProtKB:Q9WU66
determination method
IBA
Wnt-protein binding
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IBA
Wnt-activated receptor activity
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU66&geneProductId=UniProtKB:Q9WU66
determination method
IBA
cell component
extracellular region
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WU66
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IEA
integral component of membrane
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU66&geneProductId=UniProtKB:Q9WU66
determination method
IBA
extracellular space
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IBA
biological process
cell differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WU66
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IEA
negative regulation of protein kinase B signaling
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
ISO
regulation of establishment of planar polarity
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
convergent extension involved in axis elongation
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
negative regulation of Wnt signaling pathway
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
ISO
Wnt signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WU66
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IEA
negative regulation of DNA-binding transcription factor activity
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
ISO
planar cell polarity pathway involved in neural tube closure
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
multicellular organism development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9WU66
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IEA
negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
ISO
post-anal tail morphogenesis
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian duct
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
negative regulation of planar cell polarity pathway involved in axis elongation
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
negative regulation of JUN kinase activity
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
negative regulation of canonical Wnt signaling pathway
determination method
ISO
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU66&geneProductId=UniProtKB:Q9WU66
determination method
ISO
negative regulation of cell population proliferation
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
ISO
digestive tract morphogenesis
determination method
IGI
1 reference
retrieved
14 February 2019
stated in
Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IGI
regulation of Wnt signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IEA
regulation of BMP signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IEA
G protein-coupled receptor signaling pathway
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9WU66&geneProductId=UniProtKB:Q9WU66
determination method
IEA
canonical Wnt signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IBA
non-canonical Wnt signaling pathway
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IBA
negative regulation of canonical Wnt signaling pathway
determination method
IBA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
ISO
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9WU66
determination method
IBA
has part(s)
frizzled domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9WU66
Netrin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9WU66
Netrin module, non-TIMP type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9WU66
Identifiers
RefSeq protein ID
NP_061250
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
54612
UniProt protein ID
Q9WU66
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9WU66
Ensembl protein ID
ENSMUSP00000018966
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000018966
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