(Q21989254)

http://www.ebi.ac.uk/interpro/protein/P60605

Ubiquitin-conjugating enzyme E2 family

1 reference

based on heuristic

inferred from protein domain or family

Ubiquitin-conjugating enzyme, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

4 references

14 February 2019

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

ubiquitin conjugating enzyme activity

IEA

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

24 April 2018

A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

24 April 2018

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

ubiquitin protein ligase binding

IDA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

ubiquitin protein ligase activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

identical protein binding

3 references

14 February 2019

Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

ubiquitin-protein transferase activity

IPI

3 references

ubiquitin conjugating enzyme activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s)

cell component

endoplasmic reticulum

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

1 reference

24 April 2018

Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

protein K48-linked ubiquitination

IDA

biological process

3 references

protein polyubiquitination

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

protein N-linked glycosylation via asparagine

3 references

ubiquitin-dependent ERAD pathway

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

24 April 2018

Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P60605&geneProductId=UniProtKB:P60605

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

IDA

protein ubiquitination

1 reference

14 February 2019

ubiquitin-dependent protein catabolic process

IEA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

ubiquitin-dependent ERAD pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60605

Ubiquitin-conjugating enzyme, active site

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P60605

Ubiquitin-conjugating enzyme E2

1 reference

stated in

InterPro Release 71.0