(Q21989344)

English

Pericentrin (kendrin)

mammalian protein found in Mus musculus

pericentrin 2
pericentrin-250
Pcnt
pericentrin
pericentrin-360

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

A-kinase anchor protein 9/Pericentrin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48725

Pericentrin/AKAP-450 centrosomal targeting domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

calmodulin binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

protein binding

determination method

5 references

9 May 2019

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

molecular adaptor activity

determination method

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

determination method

9 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Large-scale identification of mammalian proteins localized to nuclear sub-compartments

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

pericentriolar material

determination method

1 reference

9 May 2019

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

cis-Golgi network

determination method

1 reference

9 May 2019

Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

centriolar satellite

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

microtubule organizing center

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

intercellular bridge

determination method

1 reference

9 May 2019

Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

determination method

3 references

9 May 2019

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

9 May 2019

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

determination method

1 reference

9 May 2019

Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

biological process

positive regulation of intracellular protein transport

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

limb morphogenesis

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

kidney development

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

multicellular organism growth

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

mitotic spindle organization

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

head development

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

negative regulation of apoptotic process

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

neuron migration

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

in utero embryonic development

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

embryonic heart tube development

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

vasculature development

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

spindle organization

determination method

1 reference

9 May 2019

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

embryonic brain development

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

cerebellar cortex morphogenesis

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

neural precursor cell proliferation

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

camera-type eye development

determination method

1 reference

9 May 2019

A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

olfactory bulb development

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

microtubule cytoskeleton organization

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

brain morphogenesis

determination method

1 reference

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

cilium assembly

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

signal transduction

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48725

determination method

Pericentrin/AKAP-450 centrosomal targeting domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48725

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000001179

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000001179

ENSMUSP00000151534

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000151534

ENSMUSP00000151981

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000151981

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