Wikidata

(Q21989355)

English

Pancreatic and duodenal homeobox 1

mammalian protein found in Mus musculus

  • IDX-1
  • pancreatic and duodenal homeobox gene 1
  • islet/duodenum homeobox 1
  • STF-1
  • insulin promoter factor 1, homeodomain transcription factor
  • pancreas/duodenum homeobox protein 1
  • Pdx1
  • somatostatin-transactivating factor 1
  • Insulin promoter factor 1
  • IPF-1
In more languages
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No label defined

No description defined

Statements

molecular function
DNA binding
determination method or standard
IDA
IEA
6 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P52946
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
14 February 2019
stated in
The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
cell component
nucleus
determination method or standard
IDA
IEA
ISO
11 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P52946
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
24 April 2018
stated in
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
Pdx1-related homeodomain transcription factors are distinctly expressed in mouse adult pancreatic islets
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
ISO
12 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P52946
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
14 February 2019
stated in
pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Pdx1-related homeodomain transcription factors are distinctly expressed in mouse adult pancreatic islets
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IEA
ISO
5 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
24 April 2018
stated in
PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
Conserved transcriptional regulatory domains of the pdx-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
24 April 2018
stated in
Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P52946&geneProductId=UniProtKB:P52946
determination method or standard
IDA
positive regulation of transcription by RNA polymerase II
determination method or standard
IBA
IDA
IEA
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IEA
retrieved
14 February 2019
stated in
PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Conserved transcriptional regulatory domains of the pdx-1 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52946
determination method or standard
IBA

Identifiers

 
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