(Q21989641)

http://www.ebi.ac.uk/interpro/protein/P56581

Uracil-DNA glycosylase-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P56581

Uracil-DNA glycosylase-like family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein homodimerization activity

3 references

mismatched DNA binding

3 references

transcription coregulator activity

2 references

24 April 2018

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

DNA N-glycosylase activity

IGI

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

2 references

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

double-stranded DNA binding

IPI

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

3 references

protein kinase C binding

1 reference

14 February 2019

Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

1 reference

14 February 2019

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

uracil DNA N-glycosylase activity

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

1 reference

14 February 2019

Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

21 June 2018

Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

21 June 2018

Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

regulation of transcription, DNA-templated

IBA

biological process

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

regulation of gene expression, epigenetic

negative regulation of chromatin binding

1 reference

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

negative regulation of protein binding

1 reference

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

transcription, DNA-templated

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P56581&geneProductId=UniProtKB:P56581

cellular response to DNA damage stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

3 references

3 references

14 February 2019

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

2 references

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

base-excision repair, AP site formation

3 references

chromatin organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

negative regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56581

regulation of embryonic development

Uracil-DNA glycosylase-like

IMP

has part(s)

1 reference

stated in

InterPro Release 71.0