(Q21989673)

English

Tropomyosin 1, alpha

mammalian protein found in Mus musculus

Tpm1
tropomyosin 1 kappa
tropomyosin alpha-1 chain
alpha-tropomyosin
tropomyosin-1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P58771

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

structural constituent of cytoskeleton

determination method

1 reference

14 February 2019

Molecular diversity of myofibrillar proteins: gene regulation and functional significance

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

structural constituent of muscle

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58771&geneProductId=UniProtKB:P58771

determination method

protein binding

determination method

1 reference

14 February 2019

Structure of the F-actin-tropomyosin complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

cytoskeletal protein binding

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

2 references

identical protein binding

determination method

2 references

protein homodimerization activity

determination method

2 references

protein N-terminus binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

actin filament binding

determination method

disordered domain specific binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

actin filament binding

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

14 February 2019

Tropomyosin isoforms localize to distinct microfilament populations in osteoclasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

filamentous actin

determination method

1 reference

24 April 2018

Tropomyosin isoforms localize to distinct microfilament populations in osteoclasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58771&geneProductId=UniProtKB:P58771

determination method

muscle thin filament tropomyosin

determination method

1 reference

14 February 2019

Molecular diversity of myofibrillar proteins: gene regulation and functional significance

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

ruffle membrane

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

actin cytoskeleton

determination method

3 references

protein-containing complex

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

biological process

positive regulation of heart rate by epinephrine

determination method

1 reference

14 February 2019

Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

in utero embryonic development

determination method

1 reference

14 February 2019

Molecular and physiological effects of alpha-tropomyosin ablation in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

actin filament organization

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

regulation of cell shape

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

cellular response to reactive oxygen species

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

sarcomere organization

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

negative regulation of vascular associated smooth muscle cell proliferation

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

negative regulation of vascular associated smooth muscle cell migration

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

muscle filament sliding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

negative regulation of cell migration

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

ruffle organization

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

positive regulation of ATP-dependent activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

regulation of ATP-dependent activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

positive regulation of cell adhesion

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

positive regulation of stress fiber assembly

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

actin filament capping

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

cardiac muscle contraction

determination method

3 references

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58771&geneProductId=UniProtKB:P58771

determination method

21 June 2018

Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58771&geneProductId=UniProtKB:P58771

determination method

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58771&geneProductId=UniProtKB:P58771

determination method

cardiac muscle contraction

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

14 February 2019

Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58771

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000109315

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109315

ENSMUSP00000109337

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109337

ENSMUSP00000030185

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000030185

ENSMUSP00000034928

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000034928

ENSMUSP00000051888

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000051888

ENSMUSP00000109314

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109314

ENSMUSP00000109316

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109316

ENSMUSP00000109317

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109317

ENSMUSP00000109319

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109319

ENSMUSP00000109320

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109320

ENSMUSP00000109323

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109323

ENSMUSP00000109325

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109325

ENSMUSP00000109326

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109326

ENSMUSP00000109327

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109327

ENSMUSP00000109331

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109331

ENSMUSP00000109335

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109335

ENSMUSP00000138514

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000138514

ENSMUSP00000138784

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000138784

Sitelinks

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Multilingual sites(0 entries)

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