(Q21989690)

English

Vav 1 oncogene

mammalian protein found in Mus musculus

proto-oncogene vav
p95vav
vav oncogene
Vav1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

CH domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

SH2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

Dbl homology (DH) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

smooth muscle protein/calponin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Vav, PH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calmodulin-regulated spectrin-associated protein, CH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calponin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

VAV1, SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

VAV1 protein, second SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dbl homology (DH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

VAV1 protein, first SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Guanine-nucleotide dissociation stimulator, CDC24, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

guanyl-nucleotide exchange factor activity

determination method

3 references

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

protein binding

determination method

4 references

14 February 2019

Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

14 February 2019

The tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

14 February 2019

Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

14 February 2019

Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

biological process

regulation of cell size

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

G protein-coupled receptor signaling pathway

determination method

1 reference

14 February 2019

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

regulation of GTPase activity

determination method

neutrophil chemotaxis

determination method

1 reference

14 February 2019

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

reactive oxygen species metabolic process

determination method

1 reference

14 February 2019

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

immune response

determination method

1 reference

14 February 2019

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

determination method

1 reference

14 February 2019

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

integrin-mediated signaling pathway

determination method

1 reference

14 February 2019

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

regulation of Rho protein signal transduction

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

positive regulation of natural killer cell mediated cytotoxicity

determination method

1 reference

14 February 2019

Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

T cell activation

determination method

1 reference

14 February 2019

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

positive regulation of GTPase activity

determination method

1 reference

14 February 2019

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

small GTPase mediated signal transduction

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27870

determination method

Calmodulin-regulated spectrin-associated protein, CH domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

Calponin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

Dbl homology (DH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

pleckstrin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

Guanine-nucleotide dissociation stimulator, CDC24, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

VAV1, SH2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

VAV1 protein, first SH3 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

VAV1 protein, second SH3 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P27870

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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