(Q21989817)

Zinc finger, NHR/GATA-type

1 reference

liver X receptor

1 reference

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

sterol response element binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

DNA-binding transcription activator activity, RNA polymerase II-specific

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

steroid hormone receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

nuclear receptor activity

2 references

14 February 2019

Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

3 references

14 February 2019

The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Tumor suppressor Menin acts as a corepressor of LXRα to inhibit hepatic lipogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

sequence-specific DNA binding

IPI

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

retinoid X receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

protein heterodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

transcription cis-regulatory region binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

transcription factor binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

nuclear receptor coactivator activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

signaling receptor activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

RNA polymerase II transcription regulator complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of proteolysis

biological process

1 reference

14 February 2019

Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

positive regulation of triglyceride biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

positive regulation of protein metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

positive regulation of cholesterol transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

cellular lipid metabolic process

1 reference

14 February 2019

Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of secretion of lysosomal enzymes

1 reference

14 February 2019

Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

1 reference

14 February 2019

Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

response to progesterone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of macrophage activation

1 reference

14 February 2019

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

positive regulation of lipoprotein lipase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of transcription by RNA polymerase II

1 reference

24 April 2018

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

positive regulation of fatty acid biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

apoptotic cell clearance

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of pinocytosis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

fatty acid biosynthetic process

1 reference

14 February 2019

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

positive regulation of toll-like receptor 4 signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of lipid transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of inflammatory response

1 reference

24 April 2018

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

triglyceride homeostasis

IGI

positive regulation of transcription by RNA polymerase II

2 references

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

steroid hormone mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of pancreatic juice secretion

1 reference

14 February 2019

Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

intracellular receptor signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

cholesterol homeostasis

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

24 April 2018

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0Y9&geneProductId=UniProtKB:Q9Z0Y9

negative regulation of transcription by RNA polymerase II

IGI

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

multicellular organism development

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

cholesterol homeostasis

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

positive regulation of transcription by RNA polymerase II

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of inflammatory response

3 references

14 February 2019

Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

cellular response to lipopolysaccharide

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

negative regulation of cold-induced thermogenesis

1 reference

14 February 2019

Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0Y9

Nuclear hormone receptor, ligand-binding domain

IGI

has part(s)

1 reference

nuclear hormone receptor-type zinc finger

1 reference