(Q21990361)

http://www.ebi.ac.uk/interpro/protein/Q8K3Z0

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K3Z0

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K3Z0

membrane protein

1 reference

inferred from GOA cell component → membrane

NACHT nucleoside triphosphatase family

1 reference

CARD domain, protein family

1 reference

Deoxyribonuclease, TatD-related, conserved site, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

Hsp90 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

muramyl dipeptide binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

Hsp70 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

endodeoxyribonuclease activity, producing 5'-phosphomonoesters

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

peptidoglycan binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

protein-containing complex binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

basolateral plasma membrane

2 references

2 references

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

protein-containing complex

2 references

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

activation of immune response

biological process

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

protein complex oligomerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of cytokine production involved in inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

maintenance of gastrointestinal epithelium

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of dendritic cell antigen processing and presentation

1 reference

14 February 2019

Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cell-mediated cross-priming in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of macrophage apoptotic process

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of epithelial cell proliferation

1 reference

14 February 2019

Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

cellular response to peptidoglycan

1 reference

14 February 2019

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of interleukin-10 production

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of NF-kappaB transcription factor activity

1 reference

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

regulation of inflammatory response

1 reference

14 February 2019

PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of interleukin-8 production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of JNK cascade

positive regulation of nitric-oxide synthase biosynthetic process

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

response to exogenous dsRNA

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of humoral immune response mediated by circulating immunoglobulin

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of interleukin-2 production

1 reference

14 February 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of oxidoreductase activity

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of interleukin-1 beta production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of interleukin-6 production

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of tumor necrosis factor production

1 reference

14 February 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of prostaglandin-endoperoxide synthase activity

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of B cell activation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of I-kappaB kinase/NF-kappaB signaling

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

positive regulation of interleukin-12 production

4 references

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

immunoglobulin production involved in immunoglobulin-mediated immune response

innate immune response

3 references

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of phosphatidylinositol 3-kinase activity

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of interleukin-18 production

1 reference

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of ERK1 and ERK2 cascade

3 references

14 February 2019

TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

macrophage inflammatory protein-1 alpha production

1 reference

14 February 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

nucleotide-binding oligomerization domain containing 2 signaling pathway

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of interleukin-12 production

3 references

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of stress-activated MAPK cascade

positive regulation of antibacterial peptide biosynthetic process

1 reference

14 February 2019

Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of tumor necrosis factor production

5 references

14 February 2019

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of protein ubiquitination

1 reference

14 February 2019

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of NF-kappaB transcription factor activity

3 references

regulation of neutrophil chemotaxis

1 reference

14 February 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

DNA metabolic process

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

immune system process

1 reference

14 February 2019

negative regulation of inflammatory response to antigenic stimulus

1 reference

14 February 2019

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of prostaglandin-E synthase activity

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

innate immune response in mucosa

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

defense response to Gram-positive bacterium

4 references

14 February 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of Notch signaling pathway

IGI

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of phagocytosis

1 reference

14 February 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of monocyte chemotactic protein-1 production

1 reference

14 February 2019

A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

detection of biotic stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of toll-like receptor 2 signaling pathway

1 reference

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

negative regulation of T cell mediated immunity

1 reference

14 February 2019

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of MAPK cascade

1 reference

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of xenophagy

1 reference

14 February 2019

TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

response to muramyl dipeptide

7 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

16 July 2018

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

positive regulation of protein K63-linked ubiquitination

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of MAP kinase activity

1 reference

14 February 2019

Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of dendritic cell cytokine production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

positive regulation of cell population proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

cellular response to lipopolysaccharide

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

response to muramyl dipeptide

ISS

8 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

11 October 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3Z0&geneProductId=UniProtKB:Q8K3Z0

intracellular signal transduction

IBA

3 references

defense response to bacterium

3 references

positive regulation of I-kappaB kinase/NF-kappaB signaling

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

response to muramyl dipeptide

IBA

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3Z0