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(Q21990395)
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English
REST corepressor 1
mammalian protein found in Mus musculus
Protein CoREST
Rcor1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8CFE3
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q8CFE3
part of
Homeobox-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8CFE3
SANT/Myb domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
ELM2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SANT domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8CFE3
encoded by
Rcor1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8CFE3
molecular function
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IEA
DNA-binding transcription repressor activity, RNA polymerase II-specific
determination method
ISO
2 references
retrieved
10 September 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
ISO
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
ISO
enzyme binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
retrieved
8 April 2019
stated in
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
retrieved
8 April 2019
stated in
Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
retrieved
8 April 2019
stated in
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
retrieved
8 April 2019
stated in
Opposing LSD1 complexes function in developmental gene activation and repression programmes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
retrieved
8 April 2019
stated in
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IPI
DNA-binding transcription factor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IBA
transcription factor binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IBA
transcription corepressor activity
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
IBA
cell component
DNA repair complex
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
The histone demethylase LSD1/KDM1A promotes the DNA damage response
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
ISO
transcription regulator complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IBA
nucleus
determination method
IBA
IEA
ISO
3 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
ISO
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IBA
transcription repressor complex
determination method
IBA
ISO
2 references
retrieved
27 February 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
ISO
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
IBA
transcription repressor complex
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
ISO
biological process
positive regulation of megakaryocyte differentiation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IMP
histone H4 deacetylation
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
ISO
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
IEA
erythrocyte differentiation
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IMP
retrieved
8 April 2019
stated in
Corepressor Rcor1 is essential for murine erythropoiesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IMP
negative regulation of transcription, DNA-templated
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
ISO
negative regulation of transcription by RNA polymerase II
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CFE3&geneProductId=UniProtKB:Q8CFE3
determination method
IBA
chromatin organization
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IEA
negative regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IEA
negative regulation of gene expression
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.
GOA
curator
UniProt
UniProt protein ID
Q8CFE3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CFE3
determination method
IDA
has part(s)
ELM2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8CFE3
SANT/Myb domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8CFE3
SANT domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8CFE3
Identifiers
RefSeq protein ID
NP_932140
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
217864
UniProt protein ID
Q8CFE3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8CFE3
Ensembl protein ID
ENSMUSP00000082034
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000082034
ENSMUSP00000112089
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000112089
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