(Q21990473)

Prospero homeobox protein 1

1 reference

Homeo-prospero domain superfamily

1 reference

Homeo-prospero domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

sequence-specific DNA binding

1 reference

14 February 2019

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

DNA-binding transcription factor activity

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

DNA-binding transcription repressor activity, RNA polymerase II-specific

NAS

1 reference

11 October 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

core promoter sequence-specific DNA binding

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

IPI

1 reference

11 October 2018

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

DNA-binding transcription factor activity, RNA polymerase II-specific

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

transcription corepressor activity

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

DNA-binding transcription repressor activity, RNA polymerase II-specific

ISO

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

10 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

PCNA interacts with Prox1 and represses its transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

Prox1 is differentially localized during lens development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

11 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

PCNA interacts with Prox1 and represses its transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Prox1 is differentially localized during lens development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

regulation of transcription, DNA-templated

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

venous blood vessel morphogenesis

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

dentate gyrus development

1 reference

14 February 2019

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

ventricular septum morphogenesis

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of forebrain neuron differentiation

1 reference

14 February 2019

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

lymphatic endothelial cell differentiation

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

positive regulation of sarcomere organization

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

Prox1 maintains muscle structure and growth in the developing heart

endocardium formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

negative regulation of transcription by RNA polymerase II

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

5 June 2018

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity

lymph vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

hepatocyte cell migration

1 reference

14 February 2019

Hepatocyte migration during liver development requires Prox1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

lens placode formation involved in camera-type eye formation

1 reference

14 February 2019

Prox1 is differentially localized during lens development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

skeletal muscle thin filament assembly

IEP

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

neuronal stem cell population maintenance

1 reference

14 February 2019

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

ventricular cardiac muscle tissue morphogenesis

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of heart growth

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of neural precursor cell proliferation

1 reference

14 February 2019

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

branching involved in pancreas morphogenesis

1 reference

14 February 2019

Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of cell cycle

1 reference

14 February 2019

Prox1 function is crucial for mouse lens-fibre elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

Hepatocyte migration during liver development requires Prox1

hepatocyte proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of cell cycle checkpoint

1 reference

14 February 2019

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

lens development in camera-type eye

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

lens morphogenesis in camera-type eye

1 reference

14 February 2019

Prox1 function is crucial for mouse lens-fibre elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

regulation of circadian rhythm

3 references

acinar cell differentiation

1 reference

14 February 2019

Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

response to nutrient levels

IEP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of cell population proliferation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

regulation of gene expression

cell fate determination

1 reference

14 February 2019

Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

endothelial cell differentiation

1 reference

14 February 2019

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity

inner ear development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

atrial cardiac muscle tissue morphogenesis

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

negative regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

ventricular cardiac myofibril assembly

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

aorta smooth muscle tissue morphogenesis

1 reference

14 February 2019

Prox1 maintains muscle structure and growth in the developing heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

cerebellar granule cell differentiation

1 reference

14 February 2019

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

negative regulation of cell population proliferation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of transcription by RNA polymerase II

1 reference

5 June 2018

Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48437&geneProductId=UniProtKB:P48437

negative regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

positive regulation of transcription by RNA polymerase II

lymphatic endothelial cell differentiation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

lens fiber cell morphogenesis

3 references

14 February 2019

Prox1 function is crucial for mouse lens-fibre elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48437

has part(s)

Homeo-prospero domain

1 reference