(Q21991170)

http://www.ebi.ac.uk/interpro/protein/O70494

Transcription factor Sp3

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O70494

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

Mammalian SP/KLF transcription factors: bring in the family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

double-stranded DNA binding

IEA

1 reference

14 February 2019

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

cis-regulatory region sequence-specific DNA binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Induction of dystrophin Dp71 expression during neuronal differentiation: opposite roles of Sp1 and AP2alpha in Dp71 promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

DNA-binding transcription repressor activity, RNA polymerase II-specific

6 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

10 September 2018

Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

24 April 2018

Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

24 April 2018

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

transcription repressor complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

megakaryocyte differentiation

IBA

biological process

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

regulation of transcription, DNA-templated

4 references

14 February 2019

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

embryonic placenta development

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

in utero embryonic development

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

Impaired hematopoiesis in mice lacking the transcription factor Sp3

monocyte differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70494&geneProductId=UniProtKB:O70494

embryonic skeletal system development

IEA

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

embryonic process involved in female pregnancy

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

Impaired hematopoiesis in mice lacking the transcription factor Sp3

T cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

granulocyte differentiation

1 reference

14 February 2019

Impaired hematopoiesis in mice lacking the transcription factor Sp3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

embryonic camera-type eye morphogenesis

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

trophectodermal cell differentiation

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

enucleate erythrocyte differentiation

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

erythrocyte differentiation

1 reference

14 February 2019

Impaired hematopoiesis in mice lacking the transcription factor Sp3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

definitive hemopoiesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

1 reference

14 February 2019

Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

Impaired hematopoiesis in mice lacking the transcription factor Sp3

B cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

negative regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

14 February 2019

Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

natural killer cell differentiation

1 reference

14 February 2019

Impaired hematopoiesis in mice lacking the transcription factor Sp3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

regulation of transcription by RNA polymerase II

IEA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70494

IBA

has part(s)

Zinc finger C2H2-type

1 reference

stated in

InterPro Release 71.0