(Q21991336)

English

Tribbles pseudokinase 1

mammalian protein found in Mus musculus

Trib1
tribbles homolog 1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Tribbles homologue 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K4K4

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K4K4

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein kinase activity

determination method

1 reference

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

ubiquitin-protein transferase regulator activity

determination method

1 reference

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

protein kinase inhibitor activity

determination method

3 references

transcription factor binding

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

mitogen-activated protein kinase kinase binding

determination method

3 references

determination method

1 reference

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

ubiquitin protein ligase binding

determination method

1 reference

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

determination method

3 references

biological process

positive regulation of macrophage differentiation

determination method

1 reference

14 February 2019

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

negative regulation of DNA-binding transcription factor activity

determination method

negative regulation of neutrophil differentiation

determination method

1 reference

14 February 2019

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

protein phosphorylation

determination method

1 reference

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

response to lipopolysaccharide

determination method

positive regulation of ubiquitin-protein transferase activity

determination method

1 reference

14 February 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

positive regulation of eosinophil differentiation

determination method

1 reference

14 February 2019

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method

1 reference

27 March 2018

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4K4&geneProductId=UniProtKB:Q8K4K4

determination method

regulation of MAP kinase activity

determination method

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method

regulation of MAP kinase activity

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4K4

determination method

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K4K4

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000068834

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000068834

ENSMUSP00000112828

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000112828

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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