(Q21991407)

Zinc finger, NHR/GATA-type

1 reference

nuclear receptor ROR

1 reference

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

24 April 2018

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

DNA-binding transcription factor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

steroid hormone receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

nuclear receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

transcription coactivator binding

IPI

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

ligand-activated transcription factor activity

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

2 references

sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

14 February 2019

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

external side of plasma membrane

TAS

1 reference

14 February 2019

The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

14 February 2019

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

interleukin-17 production

1 reference

14 February 2019

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

T cell differentiation in thymus

1 reference

14 February 2019

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

regulation of gamma-delta T cell differentiation

1 reference

14 February 2019

Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

negative regulation of thymocyte apoptotic process

1 reference

24 April 2018

RORgammat recruits steroid receptor coactivators to ensure thymocyte survival

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

circadian regulation of gene expression

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

regulation of fat cell differentiation

1 reference

14 February 2019

Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

regulation of steroid metabolic process

1 reference

14 February 2019

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

positive regulation of transcription, DNA-templated

IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells

protein phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

mucosa-associated lymphoid tissue development

1 reference

14 February 2019

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

intracellular receptor signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

regulation of glucose metabolic process

1 reference

14 February 2019

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

alpha-beta T cell differentiation

1 reference

14 February 2019

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

xenobiotic metabolic process

1 reference

14 February 2019

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

positive regulation of circadian rhythm

1 reference

14 February 2019

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

adipose tissue development

1 reference

14 February 2019

Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

T-helper 17 cell differentiation

3 references

24 April 2018

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

24 April 2018

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

24 April 2018

Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

Peyer's patch development

1 reference

24 April 2018

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

T-helper cell differentiation

1 reference

24 April 2018

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51450&geneProductId=UniProtKB:P51450

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

lymph node development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

steroid hormone mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

cellular response to sterol

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

T-helper 17 cell differentiation

ISO

1 reference

14 February 2019

Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51450

Nuclear hormone receptor, ligand-binding domain

has part(s)

1 reference

nuclear hormone receptor-type zinc finger

1 reference