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(Q21992163)
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English
T cell leukemia, homeobox 2
mammalian protein found in Mus musculus
homeobox protein Hox-11L1
Tlx2
PMUR10F
T-cell leukemia homeobox protein 2
homeo box 11-like 1
homeobox TLX-2
Hox11L.1
enteric neuron homeobox protein
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61663
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q61663
part of
Homeobox-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61663
Homeobox domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox domain, metazoa, protein family
1 reference
based on heuristic
inferred from protein domain or family
Homeobox, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61663
encoded by
Tlx2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61663
molecular function
DNA-binding transcription factor activity
determination method
ISA
1 reference
retrieved
14 February 2019
stated in
The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISA
DNA binding
determination method
ISA
IEA
3 references
retrieved
9 May 2019
stated in
The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISA
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61663
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IPI
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IEA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
sequence-specific DNA binding
determination method
IEA
ISO
3 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
DNA-binding transcription factor activity
determination method
IEA
ISA
2 references
retrieved
9 May 2019
stated in
The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
cell component
nucleus
determination method
IDA
ISA
IEA
3 references
retrieved
9 May 2019
stated in
The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISA
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61663
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
retrieved
9 May 2019
stated in
Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IDA
cytoplasm
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IDA
biological process
negative regulation of dendrite morphogenesis
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IDA
multicellular organism development
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61663
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
enteric nervous system development
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
A novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IMP
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
mesoderm formation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IMP
regulation of transcription by RNA polymerase II
determination method
ISA
1 reference
retrieved
9 May 2019
stated in
The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q61663
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61663&geneProductId=UniProtKB:Q61663
determination method
IEA
transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61663&geneProductId=UniProtKB:Q61663
determination method
IEA
positive regulation of transcription by RNA polymerase II
determination method
IEA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61663
determination method
IEA
has part(s)
Homeobox domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61663
Homeobox, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61663
Homeobox domain, metazoa
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61663
Identifiers
RefSeq protein ID
NP_033418
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
21909
UniProt protein ID
Q61663
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61663
Ensembl protein ID
ENSMUSP00000133420
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000133420
ENSMUSP00000087069
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000087069
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