(Q21992444)

http://www.ebi.ac.uk/interpro/protein/Q62351

Transferrin receptor protein 1

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62351

Transferrin receptor-like, dimerisation domain, protein family

1 reference

Transferrin receptor protein 1/2, PA domain, protein family

1 reference

PA domain, protein family

1 reference

Peptidase M28 family

1 reference

iron ion transmembrane transporter activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Transferrin receptor is necessary for development of erythrocytes and the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

transferrin receptor activity

TAS

5 references

14 February 2019

Transferrin receptor is necessary for development of erythrocytes and the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

Hsp70 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

integral component of membrane

ISO

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

4 references

14 February 2019

Role for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Novel Role of TRPML2 in the Regulation of the Innate Immune Response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

LTP requires a unique postsynaptic SNARE fusion machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

HFE-transferrin receptor complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

9 references

14 February 2019

Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

4 references

14 February 2019

A novel antimicrobial peptidoglycan recognition protein in the cornea

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Tetraspanin CD151 promotes cell migration by regulating integrin trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Snx3 regulates recycling of the transferrin receptor and iron assimilation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

perinuclear region of cytoplasm

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

3 references

external side of plasma membrane

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

Novel Role of TRPML2 in the Regulation of the Innate Immune Response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

recycling endosome membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

cellular response to extracellular stimulus

ISO

biological process

1 reference

14 February 2019

Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

cellular response to iron ion

TAS

1 reference

14 February 2019

Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

osteoclast differentiation

1 reference

14 February 2019

Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

positive regulation of bone resorption

IMP

1 reference

14 February 2019

Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

receptor-mediated endocytosis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

iron ion transmembrane transport

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

transferrin transport

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

positive regulation of B cell proliferation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

positive regulation of T cell proliferation

receptor internalization

3 references

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

14 February 2019

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351

positive regulation of isotype switching

3 references

cellular response to leukemia inhibitory factor

1 reference

14 February 2019

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62351