(Q22061955)

English

The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis

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scholarly article

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The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis (English)

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apoptotic process

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metastatic melanoma

1 reference

based on heuristic

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author name string

Christopher M Cabello

1

author given names

Christopher M.

author last names

Cabello

1 reference

Dimensions Publication ID

6 February 2023

Sarah D Lamore

2

author given names

Sarah D.

author last names

Lamore

1 reference

Dimensions Publication ID

6 February 2023

Warner B Bair

3

author given names

Warner B.

author last names

Bair

1 reference

Dimensions Publication ID

6 February 2023

Shuxi Qiao

4

author given names

Shuxi

author last names

Qiao

1 reference

Dimensions Publication ID

6 February 2023

Sara Azimian

5

author given names

Sara

author last names

Azimian

1 reference

Dimensions Publication ID

6 February 2023

Jessica L Lesson

6

author given names

Jessica L.

author last names

Lesson

1 reference

Dimensions Publication ID

6 February 2023

Georg T Wondrak

7

author given names

Georg T.

author last names

Wondrak

1 reference

Dimensions Publication ID

6 February 2023

language of work or name

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publication date

August 2012

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Investigational New Drugs

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30

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4

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1289-301

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https://scigraph.springernature.com/pub.10.1007/s10637-011-9676-7

0 references

The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

19 March 2017

Redox-directed cancer therapeutics: molecular mechanisms and opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

19 March 2017

Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

19 March 2017

DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

19 March 2017

Experimental therapeutics: targeting the redox Achilles heel of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

19 March 2017

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

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7 April 2017

Systematic review of medical treatment in melanoma: current status and future prospects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Proteomic identification of cathepsin B and nucleophosmin as novel UVA-targets in human skin fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Reactive oxygen species: an Achilles' heel of melanoma?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

The reactive oxygen-driven tumor: relevance to melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Reactive oxygen species in melanoma and its therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Redox regulation in human melanocytes and melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

12 September 2017

Dihydroartemisinin induces apoptosis by a Bak-dependent intrinsic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

The protease inhibitor, elafin, induces p53-dependent apoptosis in human melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Effect of artesunate on immune cells in ret-transgenic mouse melanoma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Melanosomal damage in normal human melanocytes induced by UVB and metal uptake--a basis for the pro-oxidant state of melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Artesunate in the treatment of metastatic uveal melanoma--first experiences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

Controlling tumor growth by modulating endogenous production of reactive oxygen species.

1 reference

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27 September 2017

Role of antioxidant genes for the activity of artesunate against tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

27 September 2017

The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

30 May 2018

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203350

30 May 2018

Artemisinin reduces human melanoma cell migration by down-regulating alpha V beta 3 integrin and reducing metalloproteinase 2 production

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9676-7

21 January 2018

Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9676-7

21 January 2018

Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9676-7

21 January 2018

Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat.

1 reference

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29 November 2018

Getting around PLX4032: studies turn up unusual mechanisms of resistance to melanoma drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/21547369

12 December 2020

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10.1007/S10637-011-9676-7

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Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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