(Q22243774)

English

Gi/o-coupled serotonin receptor activity

Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrea

  • serotonin receptor activity, coupled via Gi/o
  • 5-HT1 receptor activity
  • GO:0001586

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