(Q22244990)

English

suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling recept

  • GO:0039563
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