(Q22306443)

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Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade

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Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade (English)

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1 reference

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author name string

P. Y. Liu

1

author given names

Peter Y

author last names

Liu

1 reference

28 May 2023

Steven M Pincus

author given names

Steven M

author last names

Pincus

2

1 reference

28 May 2023

Paul Y Takahashi

author given names

Paul Y

author last names

Takahashi

3

1 reference

28 May 2023

Pamela D Roebuck

author given names

Pamela D

author last names

Roebuck

4

1 reference

28 May 2023

Ali Iranmanesh

author given names

Ali

author last names

Iranmanesh

5

1 reference

28 May 2023

Daniel M Keenan

author given names

Daniel M

author last names

Keenan

6

1 reference

28 May 2023

Johannes D Veldhuis

author given names

Johannes D

author last names

Veldhuis

7

1 reference

28 May 2023

language of work or name

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publication date

20 September 2005

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American Journal of Physiology - Endocrinology and Metabolism

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290

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1

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E34-E41

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Age-related changes in testosterone and the role of replacement therapy in older men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Transdermal dihydrotestosterone treatment of 'andropause'.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Age-related alterations in the stimulated release in vitro of catecholamines and luteinizing hormone-releasing hormone from the male rat hypothalamus.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Testosterone influences spatial cognition in older men.

2 references

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21 January 2018

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

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Effects of aging on the in vitro release of gonadotropin-releasing hormone.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements

1 reference

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21 January 2018

Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men

1 reference

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21 January 2018

Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes

1 reference

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21 January 2018

Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion

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21 January 2018

Clinical review 171: The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations

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21 January 2018

A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency

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https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

The effect of human chorionic gonadotropin on plasma steroid levels in young and old men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Two-week pulsatile gonadotropin releasing hormone infusion unmasks dual (hypothalamic and Leydig cell) defects in the healthy aging male gonadotropic axis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Radioimmunoassay of ganirelix in plasma or serum

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Approximate entropy as a measure of system complexity

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Irregularity and asynchrony in biologic network signals.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Females secrete growth hormone with more process irregularity than males in both humans and rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Hormone pulsatility discrimination via coarse and short time sampling.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Not all (possibly) "random" sequences are created equal

1 reference

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21 January 2018

Quantification of hormone pulsatility via an approximate entropy algorithm

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Randomness and degrees of irregularity

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Testosterone substitution of hypogonadal men prevents the age-dependent increases in body mass index, body fat and leptin seen in healthy ageing men: results of a cross-sectional study

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Interrelationships of serum testosterone and free testosterone index with FFM and strength in aging men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Effects of castration and gonadal steroids on serum luteinizing hormone and prolactin in old and young rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

The associations of age, lifestyle factors and chronic disease with testosterone in men: the Tromsø Study.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Acute androgen receptor blockade increases luteinizing hormone secretory activity in men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Contemporary aspects of discrete peak-detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Greater disorderliness of ACTH and cortisol release accompanies pituitary-dependent Cushing's disease.

1 reference

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21 January 2018

The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Pulsatile intravenous infusion of recombinant human luteinizing hormone under acute gonadotropin-releasing hormone receptor blockade reconstitutes testosterone secretion in young men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Erosion of endogenous testosterone-driven negative feedback on pulsatile luteinizing hormone secretion in healthy aging men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Age and testosterone feedback jointly control the dose-dependent actions of gonadotropin-releasing hormone in healthy men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Age diminishes the testicular steroidogenic response to repeated intravenous pulses of recombinant human LH during acute GnRH-receptor blockade in healthy men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Episodic luteinizing hormone (LH) secretion and the response of LH and follicle-stimulating hormone to LH-releasing hormone in aged men: evidence for coexistent primary testicular insufficiency and an impairment in gonadotropin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

21 January 2018

Age-related changes in the concentrations of cytosol receptors for sex steroid hormones in the hypothalamus and pituitary gland of the rat

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

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The gonadotropin-suppressive activity of androgen is increased in elderly men

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

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Age-related secretion of androstenedione, testosterone and dihydrotestosterone by the human testis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

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Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part I. Absolute bioavailability of 0.25 mg of ganirelix after a single subcutaneous injection in healthy female volunteers

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

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Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran). Part II. Dose-proportionality and gonadotropin suppression after multiple doses of ganirelix in healthy female volunteers

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

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Different responses of gonadotropin-releasing hormone (GnRH) release to glutamate receptor agonists during aging

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

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Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

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The influence of aging on plasma sex hormones in men: the Telecom Study

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

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Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

A biomathematical model of time-delayed feedback in the human male hypothalamic-pituitary-Leydig cell axis.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

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inferred from DOI database lookup

Neuroendocrine mechanisms by which selective Leydig cell castration unleashes increased pulsatile LH release

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

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Hypothesis testing of the aging male gonadal axis via a biomathematical construct

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

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based on heuristic

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Diminished luteinizing hormone pulse frequency and amplitude with aging in the male rat

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Fasting suppresses pulsatile luteinizing hormone (LH) secretion and enhances orderliness of LH release in young but not older men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Older men manifest multifold synchrony disruption of reproductive neurohormone outflow

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

The microdetermination of testosterone in human spermatic vein blood

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related changes in the feedback regulation of gonadotrophin secretion by sex steroids in men

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of testosterone replacement therapy on cortical and trabecular bone mineral density, vertebral body area and paraspinal muscle area in hypogonadal men

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00227.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1152/AJPENDO.00227.2005

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