(Q22316098)

English

2-oxoisovalerate dehydrogenase (acylating) activity

Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.

2-oxoisovalerate dehydrogenase activity
3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)
GO:0047101

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Statements

instance of

molecular function

1 reference

stated in

Gene Ontology release 2019-10-07

12 October 2019

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

1 reference

stated in

Gene Ontology release 2019-10-07

12 October 2019

1.2.1.25

1 reference

stated in

Gene Ontology release 2019-10-07

12 October 2019

http://purl.obolibrary.org/obo/GO_0047101

1 reference

stated in

Gene Ontology release 2019-10-07

retrieved

12 October 2019

Gene Ontology ID

GO:0047101

https://www.rhea-db.org/rhea/13997

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

has part(s)

coenzyme A(4-)

part of

left side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

3-methyl-2-oxobutanoate

part of

left side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

NAD(1−)

part of

left side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

NADH(2-)

part of

right side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

carbon dioxide

part of

right side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

isobutyryl-coenzyme A(4-)

part of

right side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

Identifiers

0 references

1 reference

Gene Ontology release 2019-10-07

12 October 2019

1 reference

inferred by common GO mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

15 June 2023

(Q22316098)

2-oxoisovalerate dehydrogenase (acylating) activity

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