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English
pyruvate dehydrogenase (NAD+) activity
Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH.
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Statements
instance of
molecular function
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
12 October 2019
Gene Ontology ID
GO:0034604
subclass of
pyruvate dehydrogenase [NAD(P)+] activity
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
12 October 2019
Gene Ontology ID
GO:0034604
part of
acetyl-CoA biosynthetic process from pyruvate
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
12 October 2019
Gene Ontology ID
GO:0034604
exact match
http://purl.obolibrary.org/obo/GO_0034604
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
11 October 2019
Gene Ontology ID
GO:0034604
https://www.rhea-db.org/rhea/28042
1 reference
reference URL
http://geneontology.org/external2go/rhea2go
has part(s)
dihydrolipoyllysine-residue acetyltransferase activity
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
12 October 2019
Gene Ontology ID
GO:0034604
dihydrolipoyl dehydrogenase activity
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
12 October 2019
Gene Ontology ID
GO:0034604
pyruvate dehydrogenase (acetyl-transferring) activity
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
12 October 2019
Gene Ontology ID
GO:0034604
NAD+
object has role
participant
1 reference
stated in
Gene Ontology release 2019-11-16
coenzyme A(4-)
part of
left side of reaction
1 reference
stated in
Gene Ontology release 2020-05-02
Rhea release 113
pyruvate ion
part of
left side of reaction
1 reference
stated in
Gene Ontology release 2020-05-02
Rhea release 113
NAD(1−)
part of
left side of reaction
1 reference
stated in
Gene Ontology release 2020-05-02
Rhea release 113
carbon dioxide
part of
right side of reaction
1 reference
stated in
Gene Ontology release 2020-05-02
Rhea release 113
acetyl-CoA(4-)
part of
right side of reaction
1 reference
stated in
Gene Ontology release 2020-05-02
Rhea release 113
NADH(2-)
part of
right side of reaction
1 reference
stated in
Gene Ontology release 2020-05-02
Rhea release 113
Identifiers
KEGG ID
R00209
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0034604
1 reference
stated in
Gene Ontology release 2019-10-07
retrieved
11 October 2019
Gene Ontology ID
GO:0034604
UMLS CUI
C2612720
1 reference
based on heuristic
inferred by common GO mappings on source and on Wikidata
stated in
UMLS 2023
retrieved
15 June 2023
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