(Q22319845)

English

pyrimidodiazepine synthase activity

Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.

PDA synthase activity
GO:0004734
pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)

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Statements

instance of

molecular function

1 reference

stated in

Gene Ontology release 2019-10-07

12 October 2019

oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor

1 reference

stated in

Gene Ontology release 2019-10-07

12 October 2019

1.5.4.1

1 reference

stated in

Gene Ontology release 2019-10-07

11 October 2019

http://purl.obolibrary.org/obo/GO_0004734

1 reference

stated in

Gene Ontology release 2019-10-07

retrieved

11 October 2019

Gene Ontology ID

GO:0004734

https://www.rhea-db.org/rhea/10720

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

has part(s)

water

part of

left side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

glutathione disulfide(2-)

part of

left side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

6-acetyl-2-amino-3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one

part of

left side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

glutathionate(1-)

part of

right side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

(R)-dyspropterin

part of

right side of reaction

1 reference

reference URL

http://geneontology.org/external2go/rhea2go

retrieved

1 February 2021

Identifiers

Gene Ontology ID

GO:0004734

1 reference

stated in

Gene Ontology release 2019-10-07

11 October 2019

1 reference

inferred by common GO mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

15 June 2023

(Q22319845)

pyrimidodiazepine synthase activity

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