(Q22326838)

English

Bre1-Rad6 ubiquitin ligase complex

A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing

  • Bre1-Rad6 complex
  • GO:1990302

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