(Q22328629)
English
mitotic spindle assembly checkpoint MAD1-MAD2 complex
A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon
- MAD1-MAD2 complex
- GO:1990728
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