(Q22675641)

http://www.ebi.ac.uk/interpro/protein/Q16658

Fascin-1

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16658

Fascin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein-macromolecule adaptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

IEA

actin filament binding

4 references

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

Intrinsic dynamic behavior of fascin in filopodia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

3 references

8 April 2019

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Migrastatin analogues target fascin to block tumour metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

1 reference

26 September 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

HDA

actin filament binding

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Intrinsic dynamic behavior of fascin in filopodia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

1 reference

26 September 2017

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

3 references

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

cell projection membrane

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

extracellular exosome

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

3 references

3 references

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

IBA

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

regulation of microvillus assembly

HDA

biological process

1 reference

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

establishment of apical/basal cell polarity

1 reference

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

regulation of actin cytoskeleton organization

1 reference

8 April 2019

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

actin filament organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

positive regulation of podosome assembly

1 reference

8 April 2019

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

actin filament bundle assembly

3 references

26 September 2017

Phosphorylation of human fascin inhibits its actin binding and bundling activities

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

Migrastatin analogues target fascin to block tumour metastasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

positive regulation of extracellular matrix disassembly

1 reference

8 April 2019

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

cell-cell junction assembly

1 reference

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

cell population proliferation

1 reference

1 January 2018

cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

positive regulation of lamellipodium assembly

TAS

1 reference

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

3 references

26 September 2017

Migrastatin analogues target fascin to block tumour metastasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

positive regulation of filopodium assembly

IEA

actin cytoskeleton organization

IMP

3 references

8 April 2019

Phosphorylation of human fascin inhibits its actin binding and bundling activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

anatomical structure morphogenesis

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16658&geneProductId=UniProtKB:Q16658

establishment or maintenance of cell polarity

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

4 references

8 April 2019

Migrastatin analogues target fascin to block tumour metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

cytokine-mediated signaling pathway

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

actin filament bundle assembly

TAS

4 references

8 April 2019

Phosphorylation of human fascin inhibits its actin binding and bundling activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Migrastatin analogues target fascin to block tumour metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16658

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16658

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016