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Destrin, actin depolymerizing factor
mammalian protein found in Homo sapiens
epididymis secretory sperm binding protein
bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP))
DSTN
destrin
epididymis luminal protein 32
actin-depolymerizing factor
ADF
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P60981
subclass of
protein
1 reference
stated in
UniProt
retrieved
1 December 2016
UniProt protein ID
P60981
part of
ADF-H/Gelsolin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60981
Destrin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60981
Actin-depolymerising factor homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P60981
encoded by
DSTN
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P60981
molecular function
actin binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IPI
actin filament binding
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
retrieved
8 April 2019
stated in
Determining the differences in actin binding by human ADF and cofilin
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IDA
retrieved
8 April 2019
stated in
Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IDA
cell component
extracellular exosome
determination method
IDA
2 references
retrieved
26 September 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60981&geneProductId=UniProtKB:P60981
determination method
IDA
retrieved
26 September 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60981&geneProductId=UniProtKB:P60981
determination method
IDA
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
actin cytoskeleton
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
cortical actin cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
26 September 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P60981&geneProductId=UniProtKB:P60981
determination method
IEA
extracellular exosome
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
HDA
biological process
actin polymerization or depolymerization
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
TAS
positive regulation of actin filament depolymerization
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
actin filament severing
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
actin filament depolymerization
determination method
IEA
IDA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
retrieved
8 April 2019
stated in
Determining the differences in actin binding by human ADF and cofilin
GOA
curator
UniProt
UniProt protein ID
P60981
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IDA
actin filament fragmentation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60981
determination method
IEA
has part(s)
Actin-depolymerising factor homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60981
Identifiers
RefSeq protein ID
NP_001011546
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11034
NP_006861
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11034
XP_011527446
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11034
UniProt protein ID
P60981
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P60981
Ensembl protein ID
ENSP00000246069
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000246069
ENSP00000476975
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000476975
ENSP00000434355
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000434355
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