(Q22680278)

English

D-dopachrome tautomerase

mammalian protein found in Homo sapiens

phenylpyruvate tautomerase II
D-dopachrome decarboxylase
DDT

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Statements

1 reference

13 November 2019

1 reference

1 December 2016

macrophage migration inhibitory factor

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P30046

Tautomerase/MIF superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P30046

Macrophage migration inhibitory factor, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

dopachrome isomerase activity

1 reference

8 April 2019

Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

TAS

D-dopachrome decarboxylase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IEA

cytokine receptor binding

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IDA

phenylpyruvate tautomerase activity

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IEA

extracellular exosome

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30046&geneProductId=UniProtKB:P30046

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30046&geneProductId=UniProtKB:P30046

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30046&geneProductId=UniProtKB:P30046

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IDA

biological process

melanin biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IEA

negative regulation of macrophage chemotaxis

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IDA

positive regulation of tumor necrosis factor production

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IDA

positive regulation of inflammatory response

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IC

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30046

determination method

IGI

has part(s)

Macrophage migration inhibitory factor, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P30046

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

21 March 2016

language of work or name

1 reference

21 March 2016

language of work or name

1 reference

21 March 2016

language of work or name

English

(Q22680278)

D-dopachrome tautomerase

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