(Q24290610)

antigen receptor-mediated signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

L Zeitlmann

1

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P Sirim

2

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E Kremmer

3

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W Kolanus

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

23 March 2001

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published in

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volume

276

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page(s)

9123-32

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issue

12

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cites work

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The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

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The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

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A kinase-independent function of Lck in potentiating antigen-specific T cell activation

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SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

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Signaling and functional properties of interleukin-16.

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Membrane-expressed HIV envelope glycoprotein heterodimer is a powerful inducer of cell death in uninfected CD4+ target cells

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Perturbation of the T4 molecule transmits a negative signal to T cells

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The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

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The roles of CD8 in cytotoxic T lymphocyte function

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The Ick protein tyrosine kinase is not involved in antibody-mediated CD4 (CDR3-loop) signal transduction that inhibits HIV-1 transcription.

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Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction

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T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70.

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A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface

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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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Alpha/beta hydrolase fold enzymes: the family keeps growing

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The alpha/beta hydrolase fold

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Anergic T lymphocytes selectively express an integrin regulatory protein of the cytohesin family

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Tim23 links the inner and outer mitochondrial membranes.

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Subcellular compartmentalization of saccharide moieties in cultured normal and malignant cells

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Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.

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Vesicles and cisternae in the trans Golgi apparatus of human fibroblasts are acidic compartments

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Neuroligin 1: a splice site-specific ligand for beta-neurexins

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Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

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Interleukin 16 and its function as a CD4 ligand

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Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

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PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

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Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

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An alternative way of CD4 and CD8 association with protein kinases of the Src family.

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Membrane compartmentation is required for efficient T cell activation.

21 January 2018

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Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms.

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CD4: a co-receptor in the immune response and HIV infection

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Eukaryotic transcription regulators derive from ancient enzymatic domains.

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Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

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CD4 augments the response of a T cell to agonist but not to antagonist ligands

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Inhibitory effect of interleukin-16 on interleukin-2 production by CD4+ T cells

21 January 2018

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Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4–receptor antagonist cinalukast☆☆☆★

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Helper T-cell development in the absence of CD4-p56 Ick association

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Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein.

21 January 2018

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