(Q24290636)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

protein C inhibitor-acrosin complex

2 November 2019

main subject

spermatogenesis

0 references

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0033282

Serpin family A member 5

1 reference

GOA release 2020-03-11

heparin binding

1 reference

Serine (or cysteine) peptidase inhibitor, clade A, member 5

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Margarethe Geiger

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Peter Carmeliet

1 reference

ORCID Public Data File 2021

Margareta Furtmüller

1 reference

ORCID Public Data File 2021

author name string

Uhrin P

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Dewerchin M

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Hilpert M

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Chrenek P

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Schöfer C

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Zechmeister-Machhart M

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Vales A

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Carmeliet P

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Binder BR

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

1 December 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

2 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

1531-1539

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

Functionally inactive protein C inhibitor in seminal plasma may be associated with infertility

2 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Protein C inhibitor secreted from activated platelets efficiently inhibits activated protein C on phosphatidylethanolamine of platelet membrane and microvesicles

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Protein C inhibitor may modulate human sperm-oocyte interactions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Characterization of semenogelin II and its molecular interaction with prostate-specific antigen and protein C inhibitor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Complexes of tissue kallikrein with protein C inhibitor in human semen and urine

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Protein C inhibitor is expressed in tubular cells of human kidney

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Inactivation of human plasma kallikrein and factor XIa by protein C inhibitor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Elucidating the structural chemistry of glycosaminoglycan recognition by protein C inhibitor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Functionally active protein C inhibitor/plasminogen activator inhibitor-3 (PCI/PAI-3) is secreted in seminal vesicles, occurs at high concentrations in human seminal plasma and complexes with prostate-specific antigen

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Molecular cloning and tissue distribution of mouse protein C inhibitor (PCI)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Protein C inhibitor. Purification from human plasma and characterization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Deficiency of protein C inhibitor in combined factor V/VIII deficiency disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Characterization of a cDNA for human protein C inhibitor. A new member of the plasma serine protease inhibitor superfamily

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Complex formation between urokinase and plasma protein C inhibitor in vitro and in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Purification and characterization of plasma protein C inhibitor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Organization of the gene coding for human protein C inhibitor (plasminogen activator inhibitor-3). Assignment of the gene to chromosome 14

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Heparin binding to protein C inhibitor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Protein C inhibitor is expressed in keratinocytes of human skin.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Developmental and genetic disorders in spermatogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Evidence for the regulation of urokinase and tissue type plasminogen activators by the serpin, protein C inhibitor, in semen and blood plasma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Urinary protein C inhibitor. Glycosaminoclycans synthesized by the epithelial kidney cell line TCL-598 enhance its interaction with urokinase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Characterization of transgenic mice that secrete functional human protein C inhibitor into the circulation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Synthesis and ultrastructural localization of protein C inhibitor in human platelets and megakaryocytes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Molecular cloning and sequence analysis of the mouse protein C inhibitor gene.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381472

Inhibition of tissue kallikrein by protein C inhibitor. Evidence for identity of protein C inhibitor with the kallikrein binding protein

29 November 2018

1 reference

12 December 2020

Rapid inhibition of the sperm protease acrosin by protein C inhibitor

1 reference

12 December 2020

Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin Complex

1 reference

12 December 2020

Effect of protein C inhibitor (PCI) on in vitro fertilization

1 reference

12 December 2020

Heparin binding of protein-C inhibitor--analysis of the effect of heparin on the interaction of protein-C inhibitor with tissue kallikrein

1 reference

12 December 2020

Immunohistochemical localization of urokinase-type plasminogen activator in Sertoli cells and tissue-type plasminogen activator in spermatogenic cells in the rat seminiferous epithelium

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI10768

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11120760%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

11120760

1 reference