(Q24290799)

English

(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord

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scholarly article

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(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord (English)

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Glutamate metabotropic receptor 8

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GOA release 2020-03-11

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

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GOA release 2020-03-11

author name string

N K Thomas

1

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R A Wright

2

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P A Howson

3

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A E Kingston

4

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D D Schoepp

5

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D E Jane

6

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language of work or name

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publication date

March 2001

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Neuropharmacology

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40

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3

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311-8

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Metabotropic glutamate receptor antagonists, like GABA(B) antagonists, potentiate dorsal root-evoked excitatory synaptic transmission at neonatal rat spinal motoneurons in vitro

1 reference

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Pharmacology and functions of metabotropic glutamate receptors

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The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations

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Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

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Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord

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Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord

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Identification of 2-amino-2-methyl-4-phosphonobutanoic acid as an antagonist at the mGlu4a receptor

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[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells

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Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors

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LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

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Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro

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Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.

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Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: an immunohistochemical study in the rat

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Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile.

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LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

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Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones

1 reference

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Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family

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Actions of phenylglycine derivatives at L-AP4 receptors in retinal ON bipolar cells

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Phenylglycine derivatives as antagonists of metabotropic glutamate receptors

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Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells

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10.1016/S0028-3908(00)00169-6

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