(Q24291394)

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Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)

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scholarly article

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Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein) (English)

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transmembrane protein

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Signaling threshold regulating transmembrane adaptor 1

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GOA release 2020-03-11

SH2 domain binding

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GOA release 2020-03-11

author name string

K I Pfrepper

1

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A Marie-Cardine

2

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L Simeoni

3

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Y Kuramitsu

4

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A Leo

5

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J Spicka

6

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I Hilgert

7

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J Scherer

8

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B Schraven

9

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language of work or name

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publication date

June 2001

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European Journal of Immunology

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31

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6

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1825-36

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T cell antigen-receptor signal transduction

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Lymphocytes with a complex: adapter proteins in antigen receptor signaling

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The role of membrane-associated adaptors in T cell receptor signalling

1 reference

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Integration of receptor-mediated signals in T cells by transmembrane adaptor proteins

1 reference

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Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells

1 reference

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

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Essential role of LAT in T cell development

1 reference

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Biochemical analysis of the CD45-p56(lck) complex in Jurkat T cells lacking expression of lymphocyte phosphatase-associated phosphoprotein

1 reference

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SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation

1 reference

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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

1 reference

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

1 reference

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T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane

1 reference

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Identification of a novel dimeric phosphoprotein (PP29/30) associated with signaling receptors in human T lymphocytes and natural killer cells

1 reference

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SH2 domains recognize specific phosphopeptide sequences

1 reference

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The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells

1 reference

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Differential interactions of the growth factor receptor-bound protein 2 N-SH3 domain with son of sevenless and dynamin. Potential role in the Ras-dependent signaling pathway

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Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin

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Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

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1 reference

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21 January 2018

Identifiers

10.1002/1521-4141(200106)31:6<1825::AID-IMMU1825>3.0.CO;2-V

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release_6zxgg6x6ina6vfm5h7fjtt64ki

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