(Q24291716)

2

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R Ghirlando

3

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J Lund

4

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S P Young

5

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M Goodall

6

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R Jefferis

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

7 December 2001

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published in

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volume

276

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page(s)

45539-47

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issue

49

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cites work

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Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fc gamma receptor

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Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

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The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms.

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Phagocytosis mediated by three distinct Fc gamma receptor classes on human leukocytes

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Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells

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Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications

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The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region

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High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

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Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa

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Crystal structure of the soluble form of the human fcgamma-receptor IIb: a new member of the immunoglobulin superfamily at 1.7 A resolution

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The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

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Structural basis of the interaction between IgG and fcγ receptors

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Human Fcgamma receptor IIb expressed in Escherichia coli reveals IgG binding capability

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Distribution, inducibility and biological function of the cloned and expressed human beta Fc receptor II

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Calculation of protein extinction coefficients from amino acid sequence data

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A comparative study of the N-linked oligosaccharide structures of human IgG subclass proteins

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THE ARRANGEMENT OF THE PEPTIDE CHAINS IN γ-GLOBULIN

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Rapid measurement of binding constants and heats of binding using a new titration calorimeter

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Stoichiometry and thermodynamics of the interaction between the Fc fragment of human IgG1 and its low-affinity receptor Fc gamma RIII.

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The structure of a human type III Fcgamma receptor in complex with Fc

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Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides

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Coupling of local folding to site-specific binding of proteins to DNA

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A protein structural change in aglycosylated IgG3 correlates with loss of huFc gamma R1 and huFc gamma R111 binding and/or activation

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Recognition of IgG by Fcgamma receptor. The role of Fc glycosylation and the binding of peptide inhibitors

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Clinical trials of antibody therapy

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Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.

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Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

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The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties

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Infusion of Fc gamma fragments for treatment of children with acute immune thrombocytopenic purpura.

21 January 2018

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Prevention of systemic lupus erythematosus in MRL/lpr mice by administration of an immunoglobulin-binding peptide.

21 January 2018

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Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc

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7 January 2021

Aglycosylated chimaeric human IgG3 can trigger the human phagocyte respiratory burst

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7 January 2021

Human antibody effector function

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7 January 2021

Glycosylation of human IgG-Fc: influences on structure revealed by differential scanning micro-calorimetry

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7 January 2021

Thermodynamic study of the pH-dependent interaction of chromogranin A with an intraluminal loop peptide of the inositol 1,4,5-trisphosphate receptor

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7 January 2021

Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein

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7 January 2021

Expression and characterization of truncated forms of humanized L243 IgG1. Architectural features can influence synthesis of its oligosaccharide chains and affect superoxide production triggered through human Fcgamma receptor I

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7 January 2021

Oligosaccharide-protein interactions in IgG can modulate recognition by Fc gamma receptors

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7 January 2021