(Q24291855)

2

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A M Kral

3

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H W Hellinga

4

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L S Beese

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

6 November 2001

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published in

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volume

98

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issue

23

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page(s)

12948-53

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cites work

The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

All ras proteins are polyisoprenylated but only some are palmitoylated

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Protein prenylation: molecular mechanisms and functional consequences

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Farnesyl transferase inhibitors: a novel targeted tnerapy for cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Visualizing and quantifying molecular goodness-of-fit: small-probe contact dots with explicit hydrogen atoms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Protein lipidation in cell signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

p21ras is modified by a farnesyl isoprenoid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Sequence dependence of protein isoprenylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Construction of new ligand binding sites in proteins of known structure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

High level expression of mammalian protein farnesyltransferase in a baculovirus system. The purified protein contains zinc.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

NMR studies of novel inhibitors bound to farnesyl-protein transferase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60805

Bacterial expression and purification of human protein prenyltransferases using epitope-tagged, translationally coupled systems.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

Evidence for a catalytic role of zinc in protein farnesyltransferase. Spectroscopy of Co2+-farnesyltransferase indicates metal coordination of the substrate thiolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

H-Ras peptide and protein substrates bind protein farnesyltransferase as an ionized thiolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

Conformation of a heptapeptide substrate bound to protein farnesyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.241407898

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11687658

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.241407898

1 reference

ADS bibcode

2001PNAS...9812948L

0 references

1 reference

1 reference

PubMed publication ID

11687658

1 reference