(Q24293324)

GOA release 2020-03-11

author name string

Lars Mitschke

1

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Christoph Parthier

2

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Kathrin Schröder-Tittmann

3

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Johannes Coy

4

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Stefan Lüdtke

5

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Kai Tittmann

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

8 October 2010

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published in

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volume

285

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issue

41

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page(s)

31559-70

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cites work

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Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae

19 March 2017

1 reference

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Heterologous expression of human transketolase

19 March 2017

1 reference

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Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes

19 March 2017

1 reference

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Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with [...]

19 March 2017

1 reference

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Structure and Properties of an Engineered Transketolase from Maize

19 March 2017

1 reference

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Identification of catalytically important residues in yeast transketolase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Refined structure of transketolase from Saccharomyces cerevisiae at 2.0 A resolution

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Searching protein structure databases with DaliLite v.3

19 March 2017

1 reference

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Coot: model-building tools for molecular graphics

19 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

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ESPript: analysis of multiple sequence alignments in PostScript

19 March 2017

1 reference

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Transketolase haploinsufficiency reduces adipose tissue and female fertility in mice

19 March 2017

1 reference

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Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

19 March 2017

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Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming

24 March 2017

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Metabolic genes in cancer: their roles in tumor progression and clinical implications

27 September 2017

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TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization

27 September 2017

1 reference

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Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance

27 September 2017

1 reference

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High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.

27 September 2017

1 reference

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Thiamin diphosphate catalysis: enzymic and nonenzymic covalent intermediates

27 September 2017

1 reference

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Non-charged thiamine analogs as inhibitors of enzyme transketolase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Crystallization and preliminary X-ray crystallographic data with Escherichia coli transketolase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

One-substrate transketolase-catalyzed reaction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Role of thiamin (vitamin B-1) and transketolase in tumor cell proliferation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Alterations of thiamine phosphorylation and of thiamine-dependent enzymes in Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

An erythrocyte transketolase isoenzyme pattern associated with the Wernicke-Korsakoff syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Preliminary crystallographic data for transketolase from yeast.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Critical role of arg433 in rat transketolase activity as probed by site-directed mutagenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Crystallography and mutagenesis of transketolase: mechanistic implications for enzymatic thiamin catalysis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Molecular evolutionary analysis of the thiamine-diphosphate-dependent enzyme, transketolase.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Transketolase is a major protein in the mouse cornea

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

A common structural motif in thiamin pyrophosphate-binding enzymes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Transketolase A of Escherichia coli K12. Purification and properties of the enzyme from recombinant strains.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2951230

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149955

Prodrug thiamine analogs as inhibitors of the enzyme transketolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149955

Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149955

NMR analysis of covalent intermediates in thiamin diphosphate enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149955

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149955

Heterogeneous expression of transketolase in rat brain

21 January 2018

1 reference

12 December 2020

Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation

1 reference

12 December 2020

Properties and functions of the thiamin diphosphate dependent enzyme transketolase

1 reference

12 December 2020

Conserved residues are functionally distinct within transketolases of different species

1 reference

12 December 2020

Multiple sequence alignment using ClustalW and ClustalX

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.149955

7 January 2021