(Q24293401)

5-methyltetrahydrofolate-homocysteine methyltransferase

GOA release 2020-03-11

1 reference

oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Kazuhiro Yamada

1

0 references

Roy A Gravel

2

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Tetsuo Toraya

3

0 references

Rowena G Matthews

Proceedings of the National Academy of Sciences of the United States of America

4

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language of work or name

English

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publication date

20 June 2006

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published in

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volume

103

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issue

25

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page(s)

9476-81

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cites work

Human methionine synthase reductase, a soluble P-450 reductase-like dual flavoprotein, is sufficient for NADPH-dependent methionine synthase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Human methionine synthase. cDNA cloning, gene localization, and expression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Impact of cblB mutations on the function of ATP:cob(I)alamin adenosyltransferase in disorders of vitamin B12 metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Molecular dissection of human methionine synthase reductase: determination of the flavin redox potentials in full-length enzyme and isolated flavin-binding domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Failure of lysosomal release of vitamin B12: a new complementation group causing methylmalonic aciduria (cblF).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Affinity chromatography ofN5-methyltetrahydropfolate-homocysteine methyltransferase on a cobalamin-sepharose

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

The role of cobamides in methionine synthesis. Enzymatic formation of holoenzyme.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Purification and assay of cobalamin-dependent methionine synthase from Escherichia coli.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603694103

Assignment of enzymatic function to specific protein regions of cobalamin-dependent methionine synthase from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603694103

Interaction of flavodoxin with cobalamin-dependent methionine synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603694103

Electron transfer in human methionine synthase reductase studied by stopped-flow spectrophotometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603694103

Mutation and biochemical analysis of patients belonging to the cblB complementation class of vitamin B12-dependent methylmalonic aciduria

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603694103

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603694103

ENZYMATIC SYNTHESIS OF THE METHYL GROUP OF METHIONINE. VII. ISOLATION OF A COBALAMIN-CONTAINING TRANSMETHYLASE (5-METHYLTETRAHYDRO-FOLATE-HOMOCYSTEINE) FROM MAMMALIAN LIVER

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480432

Heterologous high level expression, purification, and enzymological properties of recombinant rat cobalamin-dependent methionine synthase

29 November 2018

1 reference

12 December 2020

Activation of methionine synthetase by a reduced triphosphopyridine nucleotide-dependent flavoprotein system

1 reference

12 December 2020

Formation of the N5-methyltetrahydrofolate-homocysteine methyltransferase holoenzyme from apoenzyme and adenosyl-B 12

1 reference

12 December 2020

Observations on the Organometallic Bond of the Corrinoid Coenzymes

1 reference

12 December 2020

Demonstration that mammalian methionine synthases are predominantly cobalamin-loaded

1 reference

12 December 2020

Purification and characterization of aquacobalamin reductases from mammals

1 reference

12 December 2020