(Q24293609)

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Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin

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title

Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin (English)

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main subject

Vitamin K epoxide reductase complex subunit 1

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stated in

GOA release 2020-03-11

vitamin-K-epoxide reductase (warfarin-sensitive) activity

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stated in

GOA release 2020-03-11

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1 reference

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Simone Rost

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Andreas Fregin

series ordinal

2

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Mirja Hünerberg

series ordinal

3

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Carville G Bevans

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4

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Clemens R Müller

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5

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Johannes Oldenburg

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6

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language of work or name

English

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publication date

October 2005

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published in

Thrombosis and Haemostasis

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volume

94

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issue

4

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page(s)

780-6

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Identifiers

DOI

10.1160/TH05-02-0082

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PubMed publication ID

16270630

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(Q24293609)

Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin

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