(Q24293718)

English

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

scientific article published on May 1, 1992

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scholarly article

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The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain (English)

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1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

extracellular matrix proteins

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

author name string

J. D. Sandy

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

C. R. Flannery

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

P. J. Neame

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

L. S. Lohmander

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

language of work or name

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publication date

May 1992

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full work available at URL

https://europepmc.org/articles/PMC443022

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

https://europepmc.org/articles/PMC443022?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1569188

9 October 2022

Journal of Clinical Investigation

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89

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1512-6

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5

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Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

27 September 2017

The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

27 September 2017

Role and regulation of metalloproteinases in connective tissue turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

27 September 2017

Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alternatively spliced forms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

27 September 2017

Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

27 September 2017

Markers of cartilage metabolism in arthrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

27 September 2017

Link protein as a monitor in situ of endogenous proteolysis in adult human articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

30 May 2018

Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

30 May 2018

Expression of metalloproteinases and metalloproteinase inhibitor in human arthritic synovium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

30 May 2018

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

30 May 2018

Turnover of proteoglycans in guinea pig costal cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

30 May 2018

A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

29 November 2018

The immunologic detection and characterization of cartilage proteoglycan degradation products in synovial fluids of patients with arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443022

29 November 2018

Structure of newly synthesised (35S)-proteoglycans and (35S)-proteoglycan turnover products of cartilage explant cultures from dogs with experimental osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early changes in material properties of rabbit articular cartilage after meniscectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of proteoglycan fragments in knee joint fluid after injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of increased proteoglycan turnover in cartilage explants from dogs with experimental osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/1569188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI115742

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