(Q24294709)

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Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity

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title

Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity (English)

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T Scott Reid

1

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Lorena S Beese

series ordinal

2

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language of work or name

English

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publication date

8 June 2004

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published in

Biochemistry

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volume

43

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issue

22

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page(s)

6877-84

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10.1021/BI049723B

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PubMed publication ID

15170324

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(Q24294709)

Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity

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